What are the characteristics of Down syndrome?

Some of the characteristics of Down syndrome include flat facial contours, small ears, a low nose, hung-up eyes, and low muscle tone. In addition, a single horizontal line is often seen on the palm of the hand, and the hands and fingers tend to be short.

Is there a relationship between older age at birth and risk of Down syndrome?

The risk of Down syndrome increases with maternal age. For example, a 35-year-old woman has a 1 in 385 chance of having a child with Down syndrome. This risk increases with age.

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Q: What is Down Syndrome?

Down syndrome (21 trisomy) is a genetic disorder caused by having one more chromosome 21 than normal. This often results in intellectual disability and physical developmental delays. The incidence of Down syndrome is estimated to be 1 in 700.