Regarding Postnatal DNA Sibling Testing

Postnatal Sibling DNA Testing

Postnatal sibling DNA testing is a genetic test used to determine whether two or more individuals share a biological sibling relationship. This test is often conducted when the relationship between siblings is in question or to address legal or family matters.

Sibling testing can establish a genetic relationship between siblings even in cases where the father or mother is unknown or unavailable. However, having the DNA data of a common parent allows for a more definitive conclusion.

If parental DNA information is not available, the test can only estimate the likelihood of a sibling relationship rather than provide absolute confirmation. Notably, determining sibling relationships between males is relatively straightforward due to the use of Y-chromosome analysis.

Purpose of Postnatal Sibling DNA Testing

Sibling DNA testing is used in various situations, including:

1. Inheritance Issues: Confirming sibling relationships can help resolve inheritance rights and legal disputes.
2. Family Verification: For individuals seeking scientific confirmation of family relationships, sibling DNA testing provides reliable evidence.
3. In the Absence of Parents: Even when a parent is deceased, sibling DNA testing can establish genetic relationships between siblings.

Mechanism of Sibling DNA Testing

Sibling DNA testing typically involves the analysis of Short Tandem Repeats (STRs). Since siblings inherit genetic information from their parents, those with shared parents will exhibit partial genetic matches. The degree of this match is used to determine sibling relationships.

• Full Sibling Testing: When both parents are shared, the genetic match rate between siblings is higher.
• Half Sibling Testing: When only one parent (either the father or the mother) is shared, the match rate is lower but still indicates partial genetic similarity.

Testing Procedure

1. Sample Collection: DNA samples are collected from the individuals to be tested. This is typically done using a painless and non-invasive method, such as swabbing cells from the inside of the cheek with a cotton swab.
2. DNA Analysis: The collected DNA samples are sent to a specialized testing facility for analysis. The STR (Short Tandem Repeat) regions of the DNA are examined to determine the genetic match rate between siblings.
3. Result Determination: Based on the DNA match rate, it is determined whether the individuals are full siblings, half siblings, or unrelated. Full siblings usually exhibit a very high match rate, while half siblings show a partial match. If there is no genetic relationship, no significant match will be observed.

Testing Accuracy

Sibling testing is more complex than parentage testing due to fewer shared genetic markers. However, with precise STR analysis, it is possible to determine whether individuals are full siblings or half siblings with an accuracy exceeding 99%.

Privacy and Security

Privacy is strictly protected during sibling testing. DNA samples and test results are securely handled and are not disclosed to third parties. They are only used safely for legal proceedings or personal purposes.

Applications of Sibling Testing

• Inheritance and Legal Procedures: Sibling testing is useful for proving sibling relationships to resolve inheritance disputes or legal matters.
• Family Reassurance: Scientifically confirming sibling relationships can help alleviate doubts and provide peace of mind within the family.
• In the Absence of Parents: When parents are deceased or unavailable for testing, sibling testing can confirm genetic relationships between siblings.

DNA Postnatal Sibling Testing (Private)

For private DNA postnatal sibling testing, samples are collected using non-invasive buccal swabs. A sample collection kit will be sent to your home. Simply collect the samples by swabbing the inside of the cheek and return them. Results will be delivered via email within approximately 5.5 days.

Testing Process (Private Testing)

STEP

Please contact Hiro Clinic by phone or purchase through GenerioStore.

STEP

Visit Hiro Clinic to have DNA collected from your buccal mucosa.

STEP

Send the sample along with the consent form to the Tokyo Hygiene Laboratory.

STEP

The results will be sent via email.

Legal DNA Postnatal Sibling Testing

Legal sibling testing is available at Hiro Clinic. For submission to courts or legal proceedings, legal testing is more suitable. We generally recommend opting for legal testing.

Testing Process (Legal Testing)

STEP

Please contact Hiro Clinic by phone or purchase through GenerioStore.

STEP

After visiting Hiro Clinic, DNA is collected from the buccal mucosa.
Prior to collection, identity verification is performed, and a video is recorded during the sampling process.

STEP

The sample is sent to the Tokyo Hygiene Laboratory along with the consent form.

STEP

The results will be sent via email. For legal testing only, a paper certificate with the doctor’s handwritten signature will be sent afterward.

DNA Postnatal Half-Sibling Testing

It is possible to determine the relationship between siblings who share one biological parent. By collecting DNA samples from the cheek cells of the half-siblings and the shared parent, the test can confirm whether they are half-siblings. Testing can be conducted with DNA samples from the two siblings and their common parent.

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Pricing Information

If you wish to proceed with a legal analysis, DNA collection will be conducted at Hiro Clinic under the supervision of a medical examiner. Please select the legal plan when making your purchase through GenerioStore.