What is the importance of STR in paternity testing?

The importance of STRs (short chain repeat sequences) in paternity testing is very high, and this stands out for several reasons. The main reasons are detailed below:

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High diversity and identification
Polymorphism: STRs have a high degree of polymorphism (genetic diversity among individuals) because of the different number of repeats between each individual. This makes individual identification and parent-child relationships very accurate.
Discriminating power: High polymorphism allows accurate identification of DNA profiles of different individuals.
genetic inheritance
Mendel’s laws: STRs are inherited from parent to child according to Mendel’s laws. That is, each STR allele of a child inherits one from each parent.
Confirmation of paternity: Paternity testing confirms whether a child has inherited a particular allele from its parents by comparing the alleles of specific STR markers.
Analytical Simplicity and Accuracy
Amplification by PCR: STR can be easily amplified using PCR (polymerase chain reaction), allowing analysis of even small amounts of DNA samples.
High accuracy: Modern DNA analysis techniques allow STR profiling to be performed with extremely high accuracy, detecting even the smallest differences.
Standardization and Databases
Standardization: A standard set of STR markers for forensic DNA profiling is used internationally. This facilitates comparison of results between different laboratories and countries.
Comparison with database: STR profiles are compared with the database to confirm parent-child relationships and personal identification.
Specific Uses
Paternity: Proves the parent-child relationship by comparing the STR profiles of the child and the parent and confirming the matching alleles.
Forensic: DNA samples from crime scenes are compared with those of suspects for personal identification.
Genetic research: STRs are also widely used in genealogy and population genetics studies. Forensic: DNA samples from crime scenes are compared with those of suspects for personal identification.
Summary
HIRO CLINIC offers prenatal and postnatal paternity testing using STR.