Reliable, Safe, and Fast DNA Prenatal Paternity Test
By automating the system, we have achieved the lowest price in the industry. That’s why the price is so astonishingly low!
Our fully automated system reduces labor costs, providing affordable, fast, and accurate results.
Since the testing is fully automated using barcodes from sample collection, there is no risk of sample mix-ups. Additionally, samples are sent directly from the medical facility, so there is no concern about loss.
What is the MiSeq FGx System?
This is Japan’s first DNA Prenatal Paternity Test using the MiSeq FGx System developed by Qiagen. It is the most widely used testing machine in the world. The MiSeq FGx System has been utilized globally since 2015, with a track record of over 100,000 tests. It is a machine from a highly trusted company.
Tokyo Sanitary Laboratory
The Tokyo Sanitary Laboratory is registered as a health testing facility in Japan and has dedicated doctors on staff. You can feel assured about undergoing testing at this facility, as it operates under the supervision of medical professionals.
Triple Because There Are Three Types of Samples!
With the “Triple Test” that uses three types of samples, the testing accuracy is higher than with two types of samples.
- Father’s DNA (Buccal Mucosa)
- Mother’s DNA (Buccal Mucosa)
- Fetal DNA (Maternal Blood Sample)
Comparison of Testing Locations
| Testing Period | STR (Autosomal and X Chromosome) | STR (Y Chromosome) | SNP | |
| Premium NIPPT | From 6 weeks of pregnancy | 35 | 24 | 94 |
| NIPPT | From 8 weeks of pregnancy | 28 | 24 | 0 |
The Premium NIPPT can be performed from 6 weeks of pregnancy and uses both STR and SNP for measurement.
Testing Method Using STR
Testing Method Using SNP (Single Nucleotide Polymorphism)
What is SNP?
SNP (Single Nucleotide Polymorphism) refers to locations in the DNA sequence where a single nucleotide (A, T, C, G) is replaced by another nucleotide. SNPs indicate genetic differences between individuals and are useful in genetic research and disease risk assessment.
SNPs represent minor variations in DNA and are used for paternity testing and individual identification. In paternity testing, the child’s SNP patterns are compared to those of the parents to confirm genetic relationships. SNPs are highly diverse, allowing for accurate testing even with a small amount of DNA.
For example, if a specific gene location shows:
Father: A and T combination
Mother: A and T combination
Then the child can only have the following combinations: (A, T), (A, A), or (T, T). If a combination such as (A, G) appears, it indicates that the child might have a different father.
Each gene has two SNPs because we have two chromosomes, one inherited from each parent:
A: Adenine
G: Guanine
T: Thymine
C: Cytosine
Not Applicable for Testing
Multiple Births (More than Twins)
Vanishing Twin
Limits of Testing
If the test subject has identical twins, differentiation is not possible.
Humans typically have two sets of chromosomes. Chromosomes numbered 1 through 22 are called autosomes, and there are also sex chromosomes. In total, there are 46 chromosomes. Within these chromosomes, there are regions with repeating sequences that are unique to each individual. The number of repeats varies from person to person.
For example, suppose a particular repeat in chromosome 1 appears 12 times and 13 times in the mother.
For the same location in the father, assume it appears 15 times and 17 times. The reason there are two values is that there are two copies of chromosome 1. The baby born from these two individuals will have
only four possible patterns.
If any other pattern is detected, it will be diagnosed as indicating a different father. There are more than ten variations for each location of a single gene. In the triple test, at least 22 locations are examined.
This means the probability of error is less than 111 in 102710^{27}1027, ensuring a very high level of accuracy.