与恶性肿瘤有关的基因检测
概述。
恶性肿瘤(癌症)相关基因检测是一种发现基因信息的方法,有助于诊断、治疗和预防癌症。 癌症是一种基因突变导致正常细胞失控并异常生长的疾病。 通过基因检测,我们可以了解各种癌症的特征,并制定更加个性化的治疗方案。
检查流程
寻找一家提供您所选检测项目的医疗中心。 在采集样本前,您需要预约、接受遗传咨询并填写一份同意书。 检测结果将通过电子邮件发送给您。 如有必要,将再次接受遗传咨询。
开展检查的优势。
如果您有恶性肿瘤家族史或既往史,您就可以知道自己是否有患恶性肿瘤的遗传倾向,从而提前采取预防措施。
如果是阳性呢?
强烈建议将影像检查(如 CT、MRI、PET)和血液检查(如癌症肿瘤标志物)结合起来使用,定期检查恶性肿瘤的实际和当前存在情况。 了解相关基因的名称可以使筛查更有针对性。
检查程序
使用一种特殊的 DNA 采集器从口腔黏膜内侧采集 DNA。
检查报告(如普通癌症)
检查所需时间。
从采集标本开始大约需要 4 周时间。
常见问题。
1.在哪里可以收到?
东京卫生研究所附属诊所提供检测服务。
2.什么时候可以收到?
可供检查的诊所列表中选择日期和时间。
3.如何采集标本?
来自颊粘膜
4.检测结果会丢失吗?
很少有无法测试的情况。
5.我能得到遗传方面的建议吗?
遗传专家可应要求提供咨询。 但需要额外付费。 我们按小时收费。
重点
- 口译和咨询:.
- 基因检测结果很复杂,需要专业知识。 遗传咨询师或专家的支持对于解释结果和提供咨询非常重要。
- 伦理和社会方面的考虑:.
- 基因检测还带来伦理和社会方面的挑战,如保护基因信息的隐私和防止购买保险时的歧视。
每个面板可调查的疾病列表。
每个面板可检测的基因类型。
测试名称 | 基因编号 | APC | ATM | BAP1 | BARD1 | BMPR1A | BRCA1 | BRCA2 | BRIP1 | CDH1 | CDK4 | CDKN2A | CDKN2Ap16 (INK4A) | CDKN2Ap14 (ARF) | CHEK2 | DDB2 | DICER1 | EPCAM | ERCC1 | ERCC2 | ERCC3 | ERCC4 | ERCC5 | FANCA | FANCB | FANCC | FANCD2 | FANCE | FANCF | FANCG | FANCI | FANCL | FANCM | GREM1 | HOXB13 | MEN1 | MLH1 | MRE11 | MSH2 | MSH6 | MUTYH | NBN | PALB2 | PMS2 | POLD1 | POLE | POLH | PTEN | RAD50 | RAD51C | RAD51D | RB1 | RET | SDHAF2 | SDHB | SDHC | SDHD | SLX4 | SMAD4 | SMARCA4 | STK11 | TP53 | VHL | XPA | XPC |
普通癌症套装 | 62 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | |
乳腺癌、妇科癌症 | 26 | × | 〇 | × | 〇 | × | 〇 | 〇 | 〇 | 〇 | × | × | × | × | 〇 | × | 〇 | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | × | 〇 | 〇 | 〇 | 〇 | × | × | × | × | × | × | × | 〇 | 〇 | 〇 | × | × | × | |
乳腺癌和妇科癌症(以指南为基础) | 19 | × | 〇 | × | 〇 | × | 〇 | 〇 | 〇 | 〇 | × | × | × | × | 〇 | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | × | 〇 | 〇 | 〇 | × | × | × | 〇 | × | 〇 | 〇 | × | × | × | × | × | × | × | × | × | 〇 | 〇 | × | × | × |
乳腺癌(高风险) | 7 | × | × | × | × | × | 〇 | 〇 | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | 〇 | × | × | × |
BRCA1 / BRCA2 相关 | 2 | × | × | × | × | × | 〇 | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × |
大肠癌 | 17 | 〇 | × | × | × | 〇 | × | × | × | 〇 | × | × | × | × | 〇 | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | 〇 | × | 〇 | 〇 | 〇 | × | × | 〇 | 〇 | 〇 | × | 〇 | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | × | × | × |
高风险大肠癌 | 10 | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | 〇 | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | × | × | × | × |
结肠直肠癌(非相关性息肉) | 5 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × |
大肠癌(息肉相关) | 7 | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | 〇 | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | × | × | × | × |
白血病相关 | 24 | × | 〇 | × | × | × | 〇 | 〇 | 〇 | × | × | × | × | × | × | × | × | 〇 | × | × | × | 〇 | × | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | 〇 | × | × | × | 〇 | × | 〇 | 〇 | × | × | 〇 | 〇 | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | 〇 | × | × | 〇 | × | × | × | × |
胃癌 | 14 | 〇 | × | × | × | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | 〇 | 〇 | 〇 | × | 〇 | × | 〇 | 〇 | × | × | × |
腺癌 | 15 | × | 〇 | × | × | × | 〇 | 〇 | × | × | × | × | × | × | 〇 | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | × | 〇 | 〇 | × | 〇 | 〇 | 〇 | × | × | × | 〇 | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × |
胰腺癌 | 17 | 〇 | 〇 | × | × | 〇 | 〇 | 〇 | × | × | 〇 | 〇 | 〇 | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | 〇 | × | 〇 | 〇 | × | × | 〇 | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | × | × | × |
肾癌 | 13 | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | 〇 | 〇 | × | × | × | 〇 | × | × | × | 〇 | × | × | × | × | × | 〇 | 〇 | 〇 | 〇 | × | × | × | × | 〇 | 〇 | × | × |
色素性乾皮症 | 9 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | 〇 | 〇 | 〇 | 〇 | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | 〇 |
家族性黑色素瘤 | 7 | × | × | 〇 | × | × | × | 〇 | × | × | 〇 | 〇 | 〇 | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | 〇 | × | × | × |
嗜铬细胞瘤 | 6 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | 〇 | 〇 | 〇 | 〇 | × | × | × | × | × | 〇 | × | × |
甲状旁腺癌 | 1 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × |
甲状腺癌 | 1 | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | × | 〇 | × | × | × | × | × | × | × | × | × | × | × | × |