Beginner（ビギナー）

女医ED

Relationship between true foreskin and ED

While a true foreskin generally does not directly affect erections, in some cases it can make sexual activity painful. A true foreskin is a condition in which the glans is completely covered by the foreskin and cannot be peeled by hand. This condition itself does not prevent erection, but the foreskin is so narrow that it can cause pain during erection. The mechanism of erection is by blood flowing into the corpora cavernosa of the penis and causing its tissues to swell.In the case of...
薬関連疾患

Pulmonary Hypertension and PDE5

Pulmonary Hypertension (PH) is a condition in which the blood pressure in the pulmonary arteries becomes abnormally high, which places an excessive burden on the heart and can eventually lead to heart failure. This condition occurs when the walls of the pulmonary arteries become thickened, stiffened, or narrowed, restricting blood flow. Pulmonary hypertension is characterized by symptoms such as shortness of breath during exercise, chest pain, fatigue, and dizziness. Five-year survival rates for pulmonary arterial hypertension (PAH) vary widely depending on the type of disease...
東洋と西洋における性交回数の比較治療法

What is PDE5?

The PDE5 (phosphodiesterase type 5) enzyme is an important enzyme, especially active in the smooth muscle cells of the penis, responsible for the breakdown of the molecule cGMP (cyclic guanosine monophosphate). cGMP promotes relaxation of vascular smooth muscle and increases blood flow to blood flow, thereby assisting in erection. Below is a more detailed description of the PDE5 enzyme and its biological importance. Role of PDE5 enzymeDegradation of cGMP: PDE5 is responsible for degrading cGMP, which terminates the biological effects of cGMP. cGMP is produced...