About PROFHILO
(PROFHILO)

PROFHILO, known as the next-generation hybrid hyaluronic acid, is a groundbreaking treatment. With just a few injection points, it deeply and widely disperses, targeting the root causes of facial sagging and reconstructing both the foundational structure and the texture of the skin. Imagine this treatment as a large-scale renovation of a building—not just repainting the walls but also strengthening the foundation and repairing damaged pillars, ensuring the structure lasts longer while maintaining its beauty. Despite this comprehensive concept, PROFHILO achieves natural and extensive rejuvenation with minimal injection points, activating the skin’s innate power—its most appealing feature.

Why does sagging occur?

The causes of sagging are multifaceted and can be attributed to several factors:

① Bone loss → Bones that once supported muscles, fat, and skin thin out, reducing their ability to provide adequate support. Additionally, as bone volume decreases, the skin becomes excess and loses its elasticity, causing sagging and wrinkles.
Examples: Hollow temples, sunken cheeks, under-eye bulges and shadows, loss of a defined jawline.

② Fat atop the bone diminishes, and excess fat shifts downward → Upper cheek volume decreases, and displaced fat accumulates lower down, forming lines like the nasolabial folds or bulldog lines.

③ Muscles and connective tissues weaken and stretch → Reduced support results in an overall sagging appearance.

④ Subcutaneous tissue structure becomes fragile, losing firmness and elasticity, causing excess skin to droop → Leading to issues like nasolabial folds and a sagging jawline.

With aging skin, both the foundation and the skin surface deteriorate. Addressing just one area isn’t enough to combat the ongoing effects of aging comprehensively.

Effects of PROFHILO

PROFHILO is an innovative high-concentration hyaluronic acid product, combining high-molecular and low-molecular hyaluronic acid through a unique thermal process, without the use of chemical agents like crosslinkers (which prevent decomposition of hyaluronic acid). This reduces concerns about allergies. Since its launch in Italy in 2015, PROFHILO has rapidly gained popularity and is now used in over 80 countries. With more than 500,000 reported cases and multiple awards in medical societies, PROFHILO’s efficacy and safety are globally recognized.

Why is it so popular and revolutionary?

① With just a few injection points, it spreads quickly, deeply, and widely across the surrounding skin.
PROFHILO disperses deeply and widely within minutes after injection. Unlike traditional methods that target specific wrinkles or depressions, PROFHILO achieves a smooth, natural finish without noticeable bumps or stiffness after treatment. While physical lift-ups with fillers or threads offer instant effects, PROFHILO is recommended for those who prefer a natural lift across the entire face, want to avoid noticeable treatments, or desire overall skin rejuvenation. It can also be combined with traditional fillers, thread treatments, HIFU, or Thermage for enhanced results.

② Remodeling from the damaged foundation of deep skin layers
Traditional hyaluronic acid injections are primarily used to fill wrinkles or add volume to areas like the nose or chin. In contrast, PROFHILO spreads widely and deeply from the injection points, targeting skin cells, supporting tissues, and even the structural fat layers of deep skin. It helps restore deteriorated fat tissues, promotes the production of elastin and collagen, and reconstructs the skin’s framework from within. While immediate improvements in skin texture and lifting can be noticed after injection, the remodeling process continues for about a month, gradually enhancing skin elasticity, radiance, and lift.

Two injections spaced one month apart form one course. Only five injection points per side of the face.

PROFHILO treatment requires minimal time and few clinic visits, making it highly convenient. While major skin treatments often require multiple sessions or involve downtime, PROFHILO is ideal for busy individuals or those looking to avoid downtime. For the face, only five injection points per side are needed, while for the neck, 10 points in total are sufficient. The procedure typically takes 10–15 minutes.
For first-time treatments, a second maintenance injection is performed approximately one month after the initial session. Afterward, maintenance treatments are recommended every six months to a year, depending on skin condition. PROFHILO is versatile and can be used on areas previously difficult to treat with hyaluronic acid, such as the neck, hands, arms, or scars.

Treatment Process of PROFHILO

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  Counseling

  Discuss and select the most suitable treatment tailored to each individual’s symptoms and preferences from various options.

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  Marking

  Mark the appropriate injection points for precise treatment.

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  Cooling

  The treatment is minimally painful, and special anesthesia is not required. Cooling the area beforehand further reduces discomfort and the risk of bruising.

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  Injection

  If treating the face, 10 points are injected—five on each side. The treatment takes approximately 10 minutes.

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  Skin Touch-Up

  After the treatment, you can immediately reapply sunscreen or touch up your makeup. Washing your face and taking a bath on the same day is also possible.

Downtime

PROFHILO diffuses quickly, making post-injection swelling subside much faster compared to traditional hyaluronic acid or skin booster injections. While individual results may vary, most facial swelling significantly diminishes within a few hours. For areas like the neck or hands, swelling may be slightly more pronounced and take 2–3 days to resolve. In cases of bruising, it can be concealed with makeup and generally improves within 1–2 weeks. These effects are typically mild and improve over time. If you experience any concerning symptoms, please consult our clinic.

Supervising Physician: Dr. Hiroko Oka