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Stem cell culture supernatant is a liquid containing cellular factors, growth factors, proteins, etc. secreted by stem cells, and is said to be useful for cell regeneration and repair. In this article we will introduce treatments that are said to be highly effective.
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What is stem cell culture supernatant?
Stem cell culture supernatant is the supernatant of the solution used to culture and proliferate stem cells. This includes cellular factors and growth factors secreted by stem cells in culture, as well as exosomes in the extracellular endoplasmic reticulum. This supernatant contains physiologically active substances secreted by cultured stem cells, so it is attracting attention in the medical and research fields.
The components contained in the supernatant vary depending on the type of stem cells and culture conditions, but generally include cellular factors involved in cell growth, regeneration, and repair, growth factors, cytokines, and anti-inflammatory substances. These physiologically active substances work to suppress cell proliferation and differentiation, cell death, and inflammation.
Stem cell culture supernatant is also used in fields such as stem cell therapy, regenerative medicine, and drug development. It also plays an important role in stem cell research, as it is possible to evaluate the state and function of stem cells by analyzing the components in the supernatant.
Beauty effects of stem cell culture supernatant liquid
Many of the ingredients contained in this product are related to skin moisturization and regeneration, and are expected to have beauty effects. For example, it contains hyaluronic acid, collagen, elastin, FGF (fibroblast growth factor), etc., and these ingredients are said to have the effect of improving skin firmness and elasticity, and reducing wrinkles and sagging. .
In addition, EGF (epidermal growth factor) and TGF-β (transforming growth factor-beta) have the effect of promoting skin cell proliferation and regeneration. By penetrating the skin, these ingredients can be expected to have the effect of alleviating skin diseases, tone up the skin, and restore luster.
Health effects of stem cell culture supernatant
Because it contains ingredients that promote cell regeneration and repair, it is also expected to have health benefits. For example, it contains GF (growth factors), cytokines, and IL-1 (interleukin 1), and these components have the effect of promoting cell proliferation and differentiation and activation of immune function. It is also expected to have anti-aging effects, and is said to be effective in removing active oxygen that causes cell aging.
Also, in the medical field, treatment methods using Stem cell culture supernatant are being researched. For example, it may be applied to the treatment of myocardial infarction, cerebral infarction, arthropathy, etc.Because the ingredients are highly purified, there are fewer risks such as cell transplantation, and the treatment may be safer.
Effective treatment using stem cell culture supernatant
The methods listed below are Stem cell culture supernatant. It is attracting attention as an example of a treatment method using.
Stem cell culture supernatant drip
The drip refers to drip therapy in which the drug is injected into a vein. It is hoped that the ingredients contained in this medicine will be distributed throughout the body and work to regenerate and repair cells, resulting in health maintenance and therapeutic effects.
Intravenous drips are used for anti-aging, relieving fatigue, improving immunity, and treating chronic diseases. It is said that receiving an intravenous drip promotes cell regeneration and repair, and is expected to be effective for health maintenance and treatment.
When receiving an intravenous drip, it is recommended that you receive a diagnosis and counseling at a medical institution, and then do so under the guidance of a specialist. It is also important to be careful in selecting medical institutions such as clinics and hospitals and therapists, and to receive treatment from a reliable specialist.
Combination treatment of stem cell culture supernatant and microneedle electroporation
Features and mechanism of microneedles
Microneedling is a treatment method that stimulates the regeneration of skin cells by making tiny holes in the skin surface using a device made up of thin needles of 0.5 mm or less. Microneedling is characterized by less pain and swelling due to needle insertion, and less downtime after treatment.
Effects of microneedling
Microneedles can stimulate the regeneration of skin cells and stimulate the production of collagen and elastin. This has the effect of improving skin elasticity and firmness. In addition, stimulation with microneedles also has the effect of increasing the penetration of beauty ingredients. Microneedling treatment using serums and creams containing beauty ingredients can be expected to provide skin nutrition and improve skin problems.
What is electroporation?
Electroporation is a technology that uses weak electrical stimulation to facilitate passage through cell membranes. Normally, cell membranes have the function of restricting the entry of substances from the outside, but electroporation creates temporary holes in the cell membrane, making it more permeable to substances.
Electroporation in the beauty field uses special equipment to apply weak electrical stimulation, allowing beauty ingredients to penetrate deep into the skin. Normally, a serum or gel is applied thinly to the skin surface, and an electroporation device is applied over it to provide weak electrical stimulation, allowing the beauty ingredients to penetrate deep into the skin.
This type of treatment not only increases the permeability of regular serums and gels, but can also be expected to increase the skin’s moisturizing ability and promote skin regeneration. It is also expected to improve skin firmness, shine, and texture after the treatment.
Advantages of combining treatments
Microneedling alone is a treatment that has a high effect on improving skin quality, but when combined with electroporation and beauty serum, the skin beautification effect is further enhanced. Hiro Clinic Cosmetic Dermatology/Cosmetic Surgery is currently attracting attention.
Stem cell culture supernatant treatment using a combination of electroporation, microneedling, and electroporation involves making fine holes in the epidermis to dermis layer with microneedles.Stem cell culture supernatant, apply it all over. By doing this, you can obtain a “drug delivery effect” where the ingredients directly penetrate into the dermis deep within the skin.
This effect causes Stem cell culture supernatant to easily penetrate into the skin cells stimulated by microneedles, and is expected to have the effect of promoting skin cell regeneration and repair. Also,Stem cell culture supernatant is said that it penetrates deeper into the skin and can be expected to have skin rejuvenation and beautifying effects.
Summary
Stem cell culture supernatant is a supernatant liquid obtained by decomposing artificially cultured stem cells, and is rich in ingredients that promote skin cell regeneration and cell growth. By injecting it, the ingredients can be distributed throughout the body, and it is attracting attention in the beauty and medical fields.
Also,by using it in conjunction with microneedling and electroporation, it is possible to penetrate ingredients deep into the skin and promote cell regeneration and cell proliferation.
However, Stem cell culture supernatant Intravenous drips fall under the category of medical practice and must be performed at a medical institution, and must be performed by a specialized doctor or nurse after receiving appropriate diagnosis and counseling.
Main side effects and risks of treatment using stem cell culture supernatant
- Redness, itching, and peeling of the skin
(Even if you do, the severity will be mild and will subside within a few days, but please do not touch or scratch it, and take care at home with proper sunscreen and moisturizer.) - scab
【Reference】
Japan Society for Regenerative Medicine Clinical Research – General Incorporated Association About stem cell culture supernatant
