The history of AGA (male pattern baldness) treatment has been shaped by decades of research and technological advances. Below is a chronological summary of the major developments and events.
1930s – Early Research
- 1939: Japanese dermatologist Dr. Shoji Okuda (Shoji Okuda) first attempted hair transplant surgery. His research developed a method of transplanting a small section of scalp, which became the basis for later hair transplant techniques [56†source].
1950s – Progress in the U.S.
- 1952: Dr. Norman Orentreich, an American dermatologist, proved that hair taken from a donor site continues to grow at the transplant site. This established the concept of “donor superiority” [57†source].
1980s – Emergence of Minoxidil
- 1988: Minoxidil (trade name: Rogaine) was first approved by the FDA for the treatment of AGA. Originally developed as a treatment for hypertension, minoxidil was discovered to promote hair growth as a topical drug [55†source].
1990s – Emergence of Finasteride
- 1997: Finasteride (trade name: Propecia) is approved by the FDA for the treatment of AGA. Finasteride prevents hair loss by inhibiting the production of DHT (dihydrotestosterone) [56†source].
2000’s – FUE method becomes popular
- Early 2000s: The Follicular Unit Extraction (FUE) method began to gain popularity. This method involves the extraction and transplantation of hair follicles from a donor site one by one, and has the advantages of less noticeable scarring and faster recovery compared to the conventional FUT method [57†source].
2010s – New treatments and technological advances
- 2010s: dutasteride (trade name: Avodart) is gaining attention as an AGA treatment. Dutasteride suppresses DHT production in the same way as finasteride, but is more potent [55†source].
- Robotic Assisted Hair Transplantation System: Technology has emerged that uses a high-precision robotic arm to automatically harvest and transplant hair follicles. This has improved the accuracy and efficiency of the procedure [56†source].
Summary
AGA treatment has evolved through decades of research and technological advances. Beginning with early hair transplant surgery, the advent of minoxidil and finasteride, and advances in FUE and robot-assisted technology, a wide variety of treatment options are now available.
参考文献
- Healthline: Hair Loss Treatments
- WebMD: Androgenetic Alopecia
- Mayo Clinic: Male Pattern Baldness
- American Academy of Dermatology: Male Pattern Hair Loss
