Androgenetic alopecia (AGA) is a type of hair loss that affects many men, and over-the-counter medications can be used to improve symptoms and slow the progression. Here, we will explain in detail the main over-the-counter drugs that are useful for AGA treatment and their effects.
1. Minoxidil lotion
Over-the-counter medicines can be purchased at drugstores.
Overview
Minoxidil is a topical drug widely used to treat AGA and is applied directly to the scalp. In Japan, it is sold under the brand name “Reup”.
Effect
Promote blood circulation: Minoxidil dilates blood vessels and increases blood circulation in the scalp, thereby providing adequate nutrients to the hair follicles.
Promote hair growth: Activates hair follicles and promotes hair growth. Returns resting hair follicles to the growth phase and helps new hair grow.
How to use
Application area: Apply twice a day to areas where you are concerned about thinning hair.
Dosage: Follow the dosage indicated on the product and use it appropriately.
Continuous use: Continuous use is required for effectiveness. It may take several months to see the first effects.
Side effect
Itchy or dry scalp: Some users may experience an itchy or dry scalp.
Initial hair loss: Immediately after starting treatment, hair loss may temporarily increase, as the hair growth cycle becomes more active.
2. Finasteride prescription drug
Overview
Finasteride is an effective oral drug for the treatment of AGA and suppresses the production of DHT (dihydrotestosterone). In Japan, it is sold under the brand name “Propecia.”
Effect
Inhibits DHT: Finasteride inhibits the enzyme 5α-reductase, which prevents the conversion of testosterone to DHT. This reduces the effect of DHT on hair follicles and inhibits hair loss.
Hair Maintenance and Growth: Supports existing hair growth while reducing hair loss.
How to use
How to take: Take once a day as directed by your doctor.
Continued use: Continuous use is required to maintain effectiveness. It may take several months to see results.
Side effect
Decreased libido: Some users have reported decreased libido and erectile dysfunction.
Other side effects include temporary fatigue and breast pain.
3. Dutasteride prescription drug
Overview
Dutasteride, like finasteride, is an oral drug that suppresses DHT production and is sold under the brand name “Zagaro.” It is said to be more powerful than finasteride.
Effect
Potent DHT inhibition: Dutasteride inhibits 5α-reductase more broadly than finasteride, inhibiting DHT production more effectively.
Hair Maintenance and Growth: Promotes hair maintenance and growth by reducing the effects of DHT.
How to use
How to take: Take once a day as directed by your doctor.
Continued use: Continuous use is required and it may take several months for effects to appear.
Side effect
Decreased libido: Similar to finasteride, decreased libido and erectile dysfunction have been reported.
Other side effects include temporary fatigue and breast pain.
Oral minoxidil
1. Overview
Minoxidil has a vasodilatory effect and is expected to have the effect of promoting blood flow to the scalp, delivering nutrients to the hair roots and promoting hair growth. Originally, external medicines (lotions and sprays) were common, but oral medicines have also gained attention in recent years.
2. Effect
- hair growth promotion: Minoxidil promotes the transition from the resting phase to the growth phase in the hair growth cycle, helping hair grow thicker and stronger.
- Improved blood flow: By dilating blood vessels and improving blood flow to the scalp, more nutrients and oxygen can be delivered to the hair roots.
- therapeutic effect: Hair growth effect has been seen in many patients, and it is especially effective in treating AGA and FAGA. It usually takes about 3 to 6 months to see results.
3. How to use
- common dosage: The general dose for oral minoxidil is about 2.5mg to 5mg per day, but it is important to follow your doctor’s instructions. In Japan, topical medications are the mainstream, while oral medications are prescribed by some clinics and doctors.
- Frequency of dosing: It is usually recommended to take once or twice a day. It is important to use it under the guidance of your doctor.
4. Side effects
Oral minoxidil has been reported to have side effects, so care must be taken when using it. Main side effects include:
- hirsutism: Body hair other than scalp hair may increase. Hair growth may be seen, especially on the face and limbs.
- low blood pressure: Originally used as a treatment for high blood pressure, it may lower blood pressure. If your blood pressure is too low, you may feel dizzy and tired.
- Palpitations or changes in heart rate: Some people may experience changes in heart rate or palpitations.
- Edema (swelling): Swelling may appear in the feet and hands.
- Dizziness/headache: Dizziness and headaches may be reported in association with a drop in blood pressure.
5. Precautions regarding use
- Doctor’s guidance required: Oral minoxidil has side effects, so it is important to use it according to your doctor’s prescription and guidance.
- Need to continue: Minoxidil is not a temporary effect, and its effects are maintained with continuous use. If you stop using it, hair loss may occur again.
Whether minokidil works or not varies from person to person. The strength of the action varies depending on the enzyme activity of each individual.
4. Other over-the-counter medicines and supplements Over-the-counter medicines
Zinc supplement
Overview: Zinc is a mineral necessary to maintain hair health, and a deficiency can cause hair loss.
Benefits: Zinc supplements can promote hair growth and prevent hair loss.
How to use: Follow the recommended daily intake and consume continuously.
Side effects: Overdosage may cause side effects such as nausea and diarrhea.
Biotin supplement
Overview: Biotin is a type of vitamin B group and plays an important role in maintaining hair health.
Benefits: Biotin supplements are effective in promoting hair growth and maintaining healthy hair.
How to use: Follow the recommended daily intake and consume continuously.
Side effects: There are almost no side effects if you take the right amount, but you should avoid overdosing.
5. Precautions when using over-the-counter medicines
Receive guidance from a doctor
Before using over-the-counter medications, it is important to consult a specialist and develop an appropriate treatment plan. When used under the guidance of a doctor, the risk of side effects can be minimized and treatment can be effective.
Be careful of side effects
Over-the-counter medications may have side effects. If you feel any abnormality while using it, stop using it immediately and consult a doctor.
Continued use
It is important to continue AGA treatment. It takes time for over-the-counter medications to take effect, so you need to be patient.
Understand individual differences
The effects of AGA treatment vary from person to person. Even the same drug has different effects depending on the person, so it is important to find the treatment method that is best for you.
In conclusion
Over-the-counter medications that can help treat AGA include minoxidil, finasteride, and dutasteride. When used properly, these drugs can slow the progression of hair loss and promote hair growth. When using over-the-counter medicines, be sure to seek guidance from a specialist to ensure continuous use and manage side effects. Additionally, taking supplements such as zinc and biotin can support hair health. Choose the right treatment and get your hair back healthy.
AGA treatment at Hiro Clinic
AGA (Androgenetic Alopecia) is a disease called male pattern baldness, which progresses if left untreated, so early treatment is necessary. The causes of AGA vary depending on the individual, but it is not a disease that cannot be treated. Hiro Clinic uses cutting-edge regenerative medicine technology to treat AGA. Our specialized doctors will suggest appropriate treatment methods tailored to each individual and will do their best to support your concerns.
